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Пожертвування 15 вересня 2024 – 1 жовтня 2024

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Також БЕЗЛІМТНІ завантаження (протягом 31 дня після завершення пожертвування) доступні для ВСІХ користувачів, які підтримають проект в період збору коштів до 1 жовтня 2024.

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Підтримати

Книги
Статті (41)
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Studies on the Chemical Constituents and Biological Activities of Ixeris

Zhang, Yao-Chun, He, Chun-Nian, Chew, Eng-Hui

Журнал:

Chemistry & Biodiversity

Рік:

2013

Мова:

english

Файл:

PDF, 418 KB

english, 2013

Design, Synthesis, and Biological Evaluation of Coupled Bioactive Scaffolds as Potential Anticancer Agents for Dual Targeting of Dihydrofolate Reductase and Thioredoxin Reductase

Ng, Hui-Li, Ma, Xiang, Chew, Eng-Hui, Chui, Wai-Keung

Журнал:

Journal of Medicinal Chemistry

Рік:

2017

Мова:

english

Файл:

PDF, 17.04 MB

english, 2017

Effect of Total Parenteral Nutrition on the Postoperative Outcome in Aged Patients with Gastric Cancer

Wu, Chew-Wun, Meng, H.C., Mok, King-Tong, Kung, Sung-Pao, Lin, Shiao-Hui, Liu, Wing-Yiu, P’eng, Fang-Ku

Журнал:

Digestive Surgery

Рік:

1995

Мова:

english

Файл:

PDF, 1.42 MB

english, 1995

A systematic review of nudge theories and strategies used to influence adult health behaviour and outcome in diabetes management

Heng Kwan, Yu, Cheng, Tsu Yu, Yoon, Sungwon, Ho, Lynn Yi-Ching, Huang, CalebWeihao, Chew, Eng Hui, Thumboo, Julian, Ostbye, Truls, Low, Lian Leng

Журнал:

Diabetes & Metabolism

Рік:

2020

Файл:

PDF, 481 KB

2020

Shogaols at proapoptotic concentrations induce G2/M arrest and aberrant mitotic cell death associated with tubulin aggregation

Fei-Fei Gan, Amrita A. Nagle, Xiaohui Ang, Olivia Huixian Ho, Sock-Hoon Tan, Hong Yang, Wai-Keung Chui, Eng-Hui Chew

Журнал:

Apoptosis

Рік:

2011

Мова:

english

Файл:

PDF, 693 KB

english, 2011

Pachymic acid impairs breast cancer cell invasion by suppressing nuclear factor-κB-dependent matrix metalloproteinase-9 expression

Hui Ling, Yaochun Zhang, Ka-Yun Ng, Eng-Hui Chew

Журнал:

Breast Cancer Research and Treatment

Рік:

2011

Мова:

english

Файл:

PDF, 606 KB

english, 2011

Functionalized aurones as inducers of NAD(P)H:quinone oxidoreductase 1 that activate AhR/XRE and Nrf2/ARE signaling pathways: Synthesis, evaluation and SAR

Chong-Yew Lee, Eng-Hui Chew, Mei-Lin Go

Журнал:

European Journal of Medicinal Chemistry

Рік:

2010

Мова:

english

Файл:

PDF, 806 KB

english, 2010

Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells — Evidence for cullin dimerization

Eng-Hui Chew, Thurka Poobalasingam, Christopher J. Hawkey, Thilo Hagen

Журнал:

Cellular Signalling

Рік:

2007

Мова:

english

Файл:

PDF, 1.37 MB

english, 2007

Cinnamaldehydes inhibit thioredoxin reductase and induce Nrf2: potential candidates for cancer therapy and chemoprevention

Eng-Hui Chew, Amrita A. Nagle, Yaochun Zhang, Silvia Scarmagnani, Puvithira Palaniappan, Tracey D. Bradshaw, Arne Holmgren, Andrew D. Westwell

Журнал:

Free Radical Biology and Medicine

Рік:

2010

Мова:

english

Файл:

PDF, 1.61 MB

english, 2010

Antitumor quinols: Role of glutathione in modulating quinol-induced apoptosis and identification of putative cellular protein targets

Eng-Hui Chew, Charles S. Matthews, Jihong Zhang, Andrew J. McCarroll, Thilo Hagen, Malcolm F.G. Stevens, Andrew D. Westwell, Tracey D. Bradshaw

Журнал:

Biochemical and Biophysical Research Communications

Рік:

2006

Мова:

english

Файл:

PDF, 257 KB

english, 2006

Identification of Michael Acceptor-Centric Pharmacophores with Substituents That Yield Strong Thioredoxin Reductase Inhibitory Character Correlated to Antiproliferative Activity

Gan, Fei-Fei, Kaminska, Kamila K., Yang, Hong, Liew, Chin-Yee, Leow, Pay-Chin, So, Choon-Leng, Tu, Lan N.L., Roy, Amrita, Yap, Chun-Wei, Kang, Tse-Siang, Chui, Wai-Keung, Chew, Eng-Hui

Журнал:

Antioxidants & Redox Signaling

Рік:

2013

Мова:

english

Файл:

PDF, 1.29 MB

english, 2013

Quinols as Novel Therapeutic Agents. 2. 1 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and Related Agents as Potent and Selective Antitumor Agents

Berry, Jane M., Bradshaw, Tracey D., Fichtner, Iduna, Ren, Ruobo, Schwalbe, Carl H., Wells, Geoffrey, Chew, Eng-Hui, Stevens, Malcolm F. G., Westwell, Andrew D.

Журнал:

Journal of Medicinal Chemistry

Рік:

2005

Мова:

english

Файл:

PDF, 124 KB

english, 2005

A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways

Gan, Fei-Fei, Ling, Hui, Ang, Xiaohui, Reddy, Shridhivya A., Lee, Stephanie S-H., Yang, Hong, Tan, Sock-Hoon, Hayes, John D., Chui, Wai-Keung, Chew, Eng-Hui

Журнал:

Toxicology and Applied Pharmacology

Рік:

2013

Мова:

english

Файл:

PDF, 1.35 MB

english, 2013

Antioxidant and Nrf2 inducing activities of luteolin, a flavonoid constituent in Ixeris sonchifolia Hance, provide neuroprotective effects against ischemia-induced cellular injury

Zhang, Yao-Chun, Gan, Fei-Fei, Shelar, Sandeep Balu, Ng, Ka-Yun, Chew, Eng-Hui

Журнал:

Food and Chemical Toxicology

Рік:

2013

Мова:

english

Файл:

PDF, 1.97 MB

english, 2013

3-(2-Oxoethylidene)indolin-2-one Derivatives Activate Nrf2 and Inhibit NF-κB: Potential Candidates for Chemoprevention

Nagle, Amrita A., Reddy, Shridhivya A., Bertrand, Helene, Tajima, Hisashi, Dang, Truong-Minh, Wong, Siew-Cheng, Hayes, John D., Wells, Geoffrey, Chew, Eng-Hui

Журнал:

ChemMedChem

Рік:

2014

Мова:

english

Файл:

PDF, 1.13 MB

english, 2014

Redox Sensitivity of Apoptosis Inducing Factor (AIF) to Oxidative Stress and its Regulation by Thiol Redox Systems

Shelar, Sandeep Balu, Nagle, Amrita Abhay, Chew, Eng-hui

Журнал:

Free Radical Biology and Medicine

Рік:

2012

Мова:

english

Файл:

PDF, 205 KB

english, 2012

Back Cover: 3-(2-Oxoethylidene)indolin-2-one Derivatives Activate Nrf2 and Inhibit NF-κB: Potential Candidates for Chemoprevention (ChemMedChem 8/2014)

Nagle, Amrita A., Reddy, Shridhivya A., Bertrand, Helene, Tajima, Hisashi, Dang, Truong-Minh, Wong, Siew-Cheng, Hayes, John D., Wells, Geoffrey, Chew, Eng-Hui

Журнал:

ChemMedChem

Рік:

2014

Файл:

PDF, 1.29 MB

2014

Inhibition of the Human Thioredoxin System

Carvalho, Cristina M. L., Chew, Eng-Hui, Hashemy, Seyed Isaac, Lu, Jun, Holmgren, Arne

Журнал:

Journal of Biological Chemistry

Рік:

2008

Мова:

english

Файл:

PDF, 985 KB

english, 2008

Sulforaphane and its methylcarbonyl analogs inhibit the LPS-stimulated inflammatory response in human monocytes through modulating cytokine production, suppressing chemotactic migration and phagocytosis in a NF-κB- and MAPK-dependent manner

Reddy, Shridhivya A., Shelar, Sandeep B., Dang, Truong-Minh, Lee, Baxter Neng-Cun, Yang, Hong, Ong, Siew-Min, Ng, Hui-Li, Chui, Wai-Keung, Wong, Siew-Cheng, Chew, Eng-Hui

Журнал:

International Immunopharmacology

Рік:

2015

Мова:

english

Файл:

PDF, 1.68 MB

english, 2015

A longitudinal study of non-motor symptom burden in Parkinson's disease after a transition to expert care

Prakash, Kumar M., Nadkarni, Nivedita V., Lye, Weng-Kit, Yong, Ming-Hui, Chew, Lai-Mun, Tan, Eng-King

Журнал:

Parkinsonism & Related Disorders

Рік:

2015

Мова:

english

Файл:

PDF, 402 KB

english, 2015

Sexual dysfunction is associated with postural instability gait difficulty subtype of Parkinson’s disease

Deng, Xiao, Xiao, Bin, Li, Hui-Hua, Lo, Yew-Long, Chew, Lai-Mun, Prakash, Kumar M., Tan, Eng-King

Журнал:

Journal of Neurology

Рік:

2015

Мова:

english

Файл:

PDF, 378 KB

english, 2015

Thioredoxin-dependent regulation of AIF-mediated DNA damage

Shelar, Sandeep B., Kaminska, Kamila K., Reddy, Shridhivya A., Kumar, Dilip, Tan, Chong-Teik, Yu, Victor C., Lu, Jun, Holmgren, Arne, Hagen, Thilo, Chew, Eng-Hui

Журнал:

Free Radical Biology and Medicine

Рік:

2015

Мова:

english

Файл:

PDF, 2.96 MB

english, 2015

Risk Perception and Impact of Severe Acute Respiratory Syndrome (SARS) on Work and Personal Lives of Healthcare Workers in Singapore What Can We Learn?

David Koh, Meng Kin Lim, Sin Eng Chia, Soo Meng Ko, Feng Qian, Vivian Ng, Ban Hock Tan, Kok Seng Wong, Wuen Ming Chew, Hui Kheng Tang, Winston Ng, Zainal Muttakin, Shanta Emmanuel, Ngan Phoon Fong, Ge

Журнал:

Medical Care

Рік:

2005

Мова:

english

Файл:

PDF, 1.24 MB

english, 2005

Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity

Ng, Hui-Li, Chen, Shangying, Chew, Eng-Hui, Chui, Wai-Keung

Журнал:

European Journal of Medicinal Chemistry

Рік:

2016

Мова:

english

Файл:

PDF, 1.77 MB

english, 2016

Exploration of the Antioxidant and Nrf2 Inducing Properties of a Group of Small Molecule Compounds That Mimic Peptide Inhibitors of Keap1-Nrf2 Interaction

Chew, Eng-Hui, Karuppasamy, Muthukumar, Li, Yanzhe, Lim, Mei-Yoke, Vu, Tai-Anh, Lai, Xingchen, Bertrand, Helene, Thiollier, Clarisse, Wells, Geoff

Журнал:

Free Radical Biology and Medicine

Рік:

2015

Мова:

english

Файл:

PDF, 202 KB

english, 2015

ChemInform Abstract: Studies on the Chemical Constituents and Biological Activities of Ixeris

Zhang, Yao-Chun, He, Chun-Nian, Chew, Eng-Hui

Журнал:

ChemInform

Рік:

2013

Файл:

PDF, 17 KB

2013

Risk Perception and Impact of Severe Acute Respiratory Syndrome (SARS) on Work and Personal Lives of Healthcare Workers in Singapore

Koh, David, Lim, Meng Kin, Chia, Sin Eng, Ko, Soo Meng, Qian, Feng, Ng, Vivian, Tan, Ban Hock, Wong, Kok Seng, Chew, Wuen Ming, Tang, Hui Kheng, Ng, Winston, Muttakin, Zainal, Emmanuel, Shanta, Fong,

Журнал:

Medical Care

Рік:

2005

Мова:

english

Файл:

PDF, 257 KB

english, 2005

Biological Characterization of the Anti-Tumor Properties of Novel Dual-Target Inhibitors of Dihydrofolate Reductase and Thioredoxin Reductase

Chew, Eng-Hui, Ng, Hui-Li, Kjellander, Matilda, Karuppasamy, Muthukumar, Swee-Yue Chong, Adrina, Chui, Wai-Keung, Ungerstedt, Johanna

Журнал:

Free Radical Biology and Medicine

Рік:

2016

Мова:

english

Файл:

PDF, 299 KB

english, 2016

Measurement properties of patient reported outcome measures for spondyloarthritis: A systematic review

Png, Kelly, Kwan, Yu Heng, Leung, Ying Ying, Phang, Jie Kie, Lau, Jia Qi, Lim, Ka Keat, Chew, Eng Hui, Low, Lian Leng, Tan, Chuen Seng, Thumboo, Julian, Fong, Warren, Østbye, Truls

Журнал:

Seminars in Arthritis and Rheumatism

Рік:

2018

Мова:

english

Файл:

PDF, 494 KB

english, 2018

Novel dual-targeting anti-proliferative triazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway

Gan, Fei-Fei, Zhang, Ruirui, Ng, Hui-Li, Karuppasamy, Muthukumar, Seah, Waygene, Yeap, Wei Hseun, Ong, Siew-Min, Hadadi, Eva, Wong, Siew-Cheng, Chui, Wai-Keung, Chew, Eng-Hui

Журнал:

Food and Chemical Toxicology

Рік:

2018

Мова:

english

Файл:

PDF, 3.86 MB

english, 2018

Causative organisms and outcomes of peritoneal dialysis-related peritonitis in Sarawak General Hospital, Kuching, Malaysia: a 3-year analysis

Phui, Vui Eng, Tan, Clare Hui Hong, Chen, Chee Kean, Lai, Kee Hoe, Chew, Kwek Foong, Chua, Hock Hin, Ngu, Laura Lui Sian, Hii, Lawrence Wei Soon

Журнал:

Renal Replacement Therapy

Рік:

2017

Мова:

english

Файл:

PDF, 326 KB

english, 2017

Factors Associated With Initiation of Biologics in Patients With Axial Spondyloarthritis in an Urban Asian City

Png, Wan Yu, Kwan, Yu Heng, Lee, Yi Xuan, Lim, Ka Keat, Chew, Eng Hui, Lui, Nai Lee, Tan, Chuen Seng, Thumboo, Julian, Østbye, Truls, Fong, Warren

Журнал:

JCR Journal of Clinical Rheumatology

Рік:

2018

Мова:

english

Файл:

PDF, 132 KB

english, 2018

Inhibition of Hypoxia-Inducible Factor-1α (HIF-1α) Protein Synthesis by DNA Damage Inducing Agents

Lou, Jessica Jie Wei, Chua, Yee Liu, Chew, Eng Hui, Gao, Jie, Bushell, Martin, Hagen, Thilo, Jin, Dong-Yan

Журнал:

PLoS ONE

Рік:

2010

Мова:

english

Файл:

PDF, 1.36 MB

english, 2010

Induction of Tumor Cell Death through Targeting Tubulin and Evoking Dysregulation of Cell Cycle Regulatory Proteins by Multifunctional Cinnamaldehydes

Nagle, Amrita A., Gan, Fei-Fei, Jones, Gavin, So, Choon-Leng, Wells, Geoffrey, Chew, Eng-Hui, Lebedeva, Irina V.

Журнал:

PLoS ONE

Рік:

2012

Мова:

english

Файл:

PDF, 2.80 MB

english, 2012

Validity and reliability of the ten-item Connor–Davidson Resilience Scale (CD-RISC10) instrument in patients with axial spondyloarthritis (axSpA) in Singapore

Kwan, Yu Heng, Ng, Amanda, Lim, Ka Keat, Fong, Warren, Phang, Jie Kie, Chew, Eng Hui, Lui, Nai Lee, Tan, Chuen Seng, Thumboo, Julian, Østbye, Truls, Leung, Ying Ying

Журнал:

Rheumatology International

Рік:

2019

Мова:

english

Файл:

PDF, 776 KB

english, 2019

Validity and reliability of the Assessment of Spondyloarthritis International Society Health Index in English-speaking patients with axial spondyloarthritis in Singapore

Kwan, Yu Heng, Aw, Fang Fang, Fong, Warren, Phang, Jie Kie, Kiltz, Uta, Lim, Ka Keat, Chew, Eng Hui, Lui, Nai Lee, Tan, Chuen Seng, Thumboo, Julian, Østbye, Truls, Leung, Ying Ying

Журнал:

International Journal of Rheumatic Diseases

Рік:

2019

Мова:

english

Файл:

PDF, 744 KB

english, 2019

Validity and reliability of the Assessment of Spondyloarthritis International Society Health Index in English-speaking patients with axial spondyloarthritis in Singapore

Kwan, Yu Heng, Aw, Fang Fang, Fong, Warren, Phang, Jie Kie, Kiltz, Uta, Lim, Ka Keat, Chew, Eng Hui, Lui, Nai Lee, Tan, Chuen Seng, Thumboo, Julian, Østbye, Truls, Leung, Ying Ying

Журнал:

International Journal of Rheumatic Diseases

Рік:

2019

Файл:

PDF, 744 KB

2019

Increased Activation of Default Mode Network in Early Parkinson’s With Excessive Daytime Sleepiness

Ooi, Leon Qi Rong, Wen, Ming-Ching, Ng, Samuel Yong-Ern, Chia, Nicole Shuang-Yu, Chew, Isabel Hui Min, Lee, Weiling, Xu, Zheyu, Hartono, Septian, Tan, Eng King, Chan, Ling Ling, Tan, Louis Chew-Seng

Журнал:

Frontiers in Neuroscience

Рік:

2019

Файл:

PDF, 567 KB

2019

Corrigendum: Increased Activation of Default Mode Network in Early Parkinson's With Excessive Daytime Sleepiness

Ooi, Leon Qi Rong, Wen, Ming-Ching, Ng, Samuel Yong-Ern, Chia, Nicole Shuang-Yu, Chew, Isabel Hui Min, Lee, Weiling, Xu, Zheyu, Hartono, Septian, Tan, Eng King, Chan, Ling Ling, Tan, Louis Chew-Seng

Журнал:

Frontiers in Neuroscience

Рік:

2020

Файл:

PDF, 135 KB

2020

Detection of ADTRP in circulation and its role as a novel biomarker for coronary artery disease

Ooi, Delicia Shu Qin, Ong, Sze Min, Eng, Ming Hui, Chan, Yiong Huak, Lee, Yung Seng, Low, Adrian Fatt Hoe, Chan, Mark Yan-Yee, Heng, Chew-Kiat, Rajasingh, Johnson

Журнал:

PLoS ONE

Рік:

2020

Файл:

PDF, 934 KB

2020

A systematic review of the factors associated with the initiation of biologicals in patients with rheumatological conditions

Png, Wan Yu, Kwan, Yu Heng, Lim, Ka Keat, Chew, Eng Hui, Lui, Nai Lee, Tan, Chuen Seng, Ãstbye, Truls, Thumboo, Julian, Fong, Warren

Журнал:

European Journal of Hospital Pharmacy Science and Practice

Рік:

2019

Файл:

PDF, 424 KB

2019